Carbonic anhydrase: Its biocatalytic mechanisms and functional properties for efficient CO2 capture process development. Issue 5 (10th September 2013)

• Record Type: Journal Article
• Authors: Kanth, Bashistha Kumar; Lee, Jinwon; Pack, Seung Pil
• Is Part Of: Engineering in life sciences. Volume 13:Issue 5(2013:Sep.)
• Page Start: 422
• Page End: 431
• Publication Date: 2013-09-10
• Subjects: Bioengineering -- Periodicals; 660.605
• DOI: 10.1002/elsc.201200157
• Languages: English
• ISSNs: 1618-0240

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <p>The accumulation of carbon dioxide (CO₂) is the main cause of global climate change and it is very important to develop technologies that can reduce atmospheric CO₂ level. Although several physical or chemical CO₂ capture processes are being developed, the efficiency of capture/sequestrationshould be increased. Carbonic anhydrase (CA, EC 4.2.1.1), a metalloenzyme, has been considered as an important biocatalyst for CO₂ capture system development because CA has the highest efficiency of CO₂ conversion via hydration (CO₂ + H₂O ↔ HCO₃⁻ + H⁺, <italic>k</italic>_cat: ∼10⁶ s⁻¹). In this review, biocatalytic mechanism and functional properties of CA are reviewed in terms of its distinctive CO₂ converting ability. In addition, recent applications of several CAs are presented in CO₂ capture process development. This review would present guidelines for scientists and researchers to understand CA functions and develop interest in the practical applications of CA, in particular, as biocatalytic agent for more efficient CO₂ capture process development.</p> </abstract>