A Highly Diastereoselective Three‐component Domino Reaction in Water Yielding Poly‐substituted 4, 5‐Dihydropyrroles. Issue 8 (17th June 2013)

• Record Type: Journal Article
• Authors: Tong, Guangjing; Xu, Haiwei; Fan, Wei; Jiang, Bo; Wang, Shuliang; Tu, Shujiang
• Is Part Of: Chinese journal of chemistry. Volume 31:Issue 8(2013:Aug.)
• Page Start: 1039
• Page End: 1044
• Publication Date: 2013-06-17
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1002/cjoc.201300249
• Languages: English
• ISSNs: 1001-604X

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>An efficient methodology for highly diastereoselective synthesis of poly‐substituted 4, 5‐dihydropyrrole derivatives from readily available common reactants in water has been developed. During domino processes, the formation of pyrrole skeleton and its C2‐hydroxylation and C3‐arylamination were readily achieved <italic>via</italic> metal‐free [3+2] heterocyclization in a one‐pot operation.</p> </abstract>