An Efficient Semi‐Synthetic Method to Construct Docetaxel via Sterically Crowded Linear Side Chain Esterification. Issue 1 (8th January 2013) - Shen, Xin
Abstract An efficient semi‐synthetic method was developed to construct docetaxel 1 by using N, N‐di‐Boc protected linear isoserine derivative 5 as the side chain source, in which, bulky protecting group on the nitrogen atom blocked C‐2′ position and prohibited unavoidable racemization in previous studies.