One‐pot Synthesis of Aromatic Fused 2, 3‐Dihydroindanone by Tandem Pauson‐Khand/Michael/Henry Reaction. Issue 1 (8th January 2013)

• Record Type: Journal Article
• Authors: Li, Mingming; Xing, Ping; Huang, Zuogang; Jiang, Biao
• Is Part Of: Chinese journal of chemistry. Volume 31:Issue 1(2013:Jan.)
• Page Start: 49
• Page End: 54
• Publication Date: 2013-01-08
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1002/cjoc.201201118
• Languages: English
• ISSNs: 1001-604X

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The intermolecular Pauson‐Khand reaction between 2‐ethynylbenzaldehyde and ethylene promoted by dimethyl sulfide can be utilized to synthesize 2‐(2‐formylphenyl)cyclopentenone efficiently. This compound and its derivatives undergo a cascade process of Michael addition reaction followed by Henry reaction with nitromethane to construct substituted aromatic fused 2, 3‐dihydroindanones. Furthermore, direct one‐pot synthesis of aromatic fused 2, 3‐dihydroindanones from 2‐ethynylbenzaldehyde is achieved.</p> </abstract>