Approach for the Direct Synthesis of β‐Dichlorosubstituted Acetanilides Using Iodine Trichloride (ICl3) as the Oxidant and Catalyst. Issue 4 (3rd April 2013)

• Record Type: Journal Article
• Authors: Zhang, Qing; Liu, Weibing; Chen, Cui; Tan, Liquan
• Is Part Of: Chinese journal of chemistry. Volume 31:Issue 4(2013:Apr.)
• Page Start: 453
• Page End: 455
• Publication Date: 2013-04-03
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1002/cjoc.201300007
• Languages: English
• ISSNs: 1001-604X

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A reliable method for direct synthesis of <italic>β</italic>‐dichlorosubstituted acetanilides is reported. The key transformation involves the oxidative and catalytic cleavage of a carbon‐carbon bond in the presence of iodine trichloride (ICl₃). In this protocol ICl₃ is used not only as the catalyst but also as the oxidant which widely broadens the scope of its application in organic synthetic chemistry.</p> </abstract>