Mild Metal‐Free Intramolecular Oxidative Alkylation of a Csp3H Bond Adjacent to a Nitrogen Atom: A Versatile Approach to Ring‐Fused Tetrahydroquinolines. Issue 5 (27th February 2013)

• Record Type: Journal Article
• Authors: Zhang, Gen; Wang, Shoulei; Ma, Yunxia; Kong, Weidong; Wang, Rui
• Is Part Of: Advanced synthesis & catalysis. Volume 355:Issue 5(2013)
• Page Start: 874
• Page End: 879
• Publication Date: 2013-02-27
• Subjects: Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201200731
• Languages: English
• ISSNs: 1615-4150

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A metal‐free intramolecular oxidative cross‐coupling reaction for the constructing C_{<italic>sp</italic>3}C_{<italic>sp</italic>3} bonds mediated by 2, 3‐dichloro‐5, 6‐dicyanobenzoquinone (DDQ) under mild conditions was realized for the first time. This novel strategy provides a simple, efficient, and environmentally friendly access to diverse ring‐fused tetrahydroquinoline derivatives.</p> </abstract>