Asymmetric α‐Amination of Aldehydes by a Recyclable Resin‐Supported Peptide Catalyst. Issue 2 (16th January 2013)

• Record Type: Journal Article
• Authors: Tanaka, Tatsuyoshi; Akagawa, Kengo; Mitsuda, Masaru; Kudo, Kazuaki
• Is Part Of: Advanced synthesis & catalysis. Volume 355:Issue 2/3(2013)
• Page Start: 294
• Page End: 296
• Publication Date: 2013-01-16
• Subjects: Catalysis -- Periodicals; Organic compounds -- Synthesis -- Periodicals; Chemistry -- Periodicals; Chemistry, Technical -- Periodicals; Chemistry -- Periodicals; Catalysis -- Periodicals; Technology, Pharmaceutical -- Periodicals; 547.2
• DOI: 10.1002/adsc.201200611
• Languages: English
• ISSNs: 1615-4150

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The asymmetric α‐amination of aldehydes was performed using a resin‐supported peptide catalyst. A tri‐ or tetrapeptide with an N‐terminal <sc>D</sc>‐Pro‐Aib sequence efficiently catalyzed the reaction in a highly enantioselective manner. The supported catalyst could be easily recovered by filtration and reused at least ten times.</p> </abstract>