Drug Delivery: Lipid‐Modified Aminoglycoside Derivatives for In Vivo siRNA Delivery (Adv. Mater. 33/2013). (3rd September 2013)

• Record Type: Journal Article
• Authors: Zhang, Yunlong; Pelet, Jeisa M.; Heller, Daniel A.; Dong, Yizhou; Chen, Delai; Gu, Zhen; Joseph, Brian J.; Wallas, Jasmine; Anderson, Daniel G.
• Is Part Of: Advanced materials. Volume 25:Number 33(2013)
• Page Start: 4680
• Page End: 4680
• Publication Date: 2013-09-03
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201370207
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>The self‐assembled nanoparticles for siRNA delivery with lipid‐modified aminoglycoside derivatives is described by Daniel G. Anderson and co‐workers <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">on page 4641</ext-link>. The core‐shell nanoparticles can protect siRNA from enzymatic degradation within the body and subsequently deliver siRNA into cytoplasm of target cells. The image is courtesy of Dr. Ning Zhang. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36gzqq2r" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>