Non‐Viral Gene Delivery via Membrane‐Penetrating, Mannose‐Targeting Supramolecular Self‐Assembled Nanocomplexes (Adv. Mater. 22/2013). (10th June 2013)

• Record Type: Journal Article
• Authors: Yin, Lichen; Song, Ziyuan; Kim, Kyung Hoon; Zheng, Nan; Gabrielson, Nathan P.; Cheng, Jianjun
• Is Part Of: Advanced materials. Volume 25:Number 22(2013)
• Page Start: 3062
• Page End: 3062
• Publication Date: 2013-06-10
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201370148
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Supramolecular self‐assembled nanocomplexes allow mannose receptormediated endocytosis and mediate membrane transduction via the pore formation mechanism, which facilitates effective cellular internalization and endosomal escape towards highly effective gene transfection, as reported by Jianjun Cheng and co‐workers <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">on page 3063</ext-link>. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg21kq6457" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>