ChemInform Abstract: Coupling Biocatalysis and Click Chemistry: One‐Pot Two‐Step Convergent Synthesis of Enantioenriched 1, 2, 3‐Triazole‐Derived Diols. Issue 28 (21st June 2013)

• Record Type: Journal Article
• Authors: Cuetos, Anibal; Bisogno, Fabricio R.; Lavandera, Ivan; Gotor, Vicente
• Is Part Of: ChemInform. Volume 44:Issue 28(2013)
• Page Start: no
• Page End: no
• Publication Date: 2013-06-21
• Subjects: Chemistry -- Abstracts -- Periodicals; 540.5
• DOI: 10.1002/chin.201328135
• Languages: English
• ISSNs: 0931-7597

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>A one‐pot synthesis of different enantiopure 1, 2, 3‐triazole‐derived diols (III) and (V) in high yields and excellent enantio‐ and stereoselectivities is achieved under mild conditions in aqueous medium by combining a single alcohol dehydrogenase with a Cu‐catalyzed "Click"‐reaction.</p> </abstract>