Biochemical and Physical Signal Gradients in Hydrogels to Control Stem Cell Behavior. (25th August 2013)

• Record Type: Journal Article
• Authors: Jeon, Oju; Alt, Daniel S.; Linderman, Stephen W.; Alsberg, Eben
• Is Part Of: Advanced materials. Volume 25:Number 44(2013)
• Page Start: 6366
• Page End: 6372
• Publication Date: 2013-08-25
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201302364
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en" id="adma201302364-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Three‐dimensional (3D) gradients</bold> of biochemical and physical signals in macroscale degradable hydrogels are engineered that can regulate photoencapsulated human mesenchymal stem cell (hMSC) behavior. This simple, cytocompatible, and versatile gradient system may be a valuable tool for researchers in biomaterials science to control stem cell fate in 3D and guide tissue regeneration. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg3z2vx13w" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>