Three‐Dimensional Microscaffolds Exhibiting Spatially Resolved Surface Chemistry. (4th September 2013) - Richter, Benjamin
Abstract Spatial control over the surface chemistry of 3D organic–inorganic hybrid microscaffolds is achieved by a two‐photon‐triggered cycloaddition. Following a coating step with photoactivatable dienes via silanization, surface irradiation with a femtosecond‐pulsed laser in the presence of functional dienophiles enables a site‐selective alteration of the surface chemistry. Bioconjugation with fluorescent protein tags is employed to reveal the 3D molecular patterns.