Hydrogel Micropillars with Integrin Selective Peptidomimetic Functionalized Nanopatterned Tops: A New Tool for the Measurement of Cell Traction Forces Transmitted through αvβ3‐ or α5β1‐Integrins. (5th August 2013) - Rahmouni, Sabri
Abstract Poly(ethylene glycol) micropillars with gold nanopatterns on top are functionalized with two integrin selective ligands. This platform is a powerful new tool to determine the specific contribution of traction forces involved in cell adhesion mediated by α5 β1‐ and αvβ3‐ integrins. Cells adherent via α5 β1‐integrins have a tendency to exert higher maximum forces than cells adhering via αvβ3‐integrins.