A Triggered DNA Hydrogel Cover to Envelop and Release Single Cells. (9th July 2013)

• Record Type: Journal Article
• Authors: Jin, Juan; Xing, Yongzheng; Xi, Yanli; Liu, Xueli; Zhou, Tao; Ma, Xinxin; Yang, Zhongqiang; Wang, Shutao; Liu, Dongsheng
• Is Part Of: Advanced materials. Volume 25:Number 34(2013)
• Page Start: 4714
• Page End: 4717
• Publication Date: 2013-07-09
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adma.201301175
• Languages: English
• ISSNs: 0935-9648

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>We develop an enzyme‐triggered permeable DNA hydrogel cover</bold> to envelop and release single cells in microwells. The porous structure of the DNA hydrogel allows nutrients and waste to pass through, leading to a cell viability as high as 98%. The design provides a general method to culture, monitor, and manipulate single cells, and has potential applications in cell patterning and studying cell communication. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36gzwr4s" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>