Glucosamine‐Conjugated Nanoparticles for the Separation of Insulin‐Secreting Beta Cells. Issue 9 (8th March 2013)

• Record Type: Journal Article
• Authors: Narayanan, Karthikeyan; Lin, Alex W. H.; Zheng, Yuangang; Erathodiyil, Nandanan; Wan, Andrew C. A.; Ying, Jackie Y.
• Is Part Of: Advanced healthcare materials. Volume 2:Issue 9(2013:Sep.)
• Page Start: 1198
• Page End: 1203
• Publication Date: 2013-03-08
• Subjects: Biomedical materials -- Periodicals; 610.28
• DOI: 10.1002/adhm.201200479
• Languages: English
• ISSNs: 2192-2640

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>A small molecule, glucosamine, is used as targeting moiety for insulin‐secreting beta cell separation</bold> in artificial cell mixtures and tissue samples. The specificity of glucosamine allows it to be used in cell sorting applications. In addition, a thrombin‐specific cleavable peptide was used as an intermediary to release nanoparticles from cell surfaces to facilitate cell attachment and proliferation. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36grx4qn" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>