Platinum(II) Catalyzed Enantioselective Cycloisomerizations of 3‐Hydroxylated 1, 5‐Enynes. Issue 7 (25th March 2013)

• Record Type: Journal Article
• Authors: Zhang, Yang; Jullien, Hélène; Brissy, Delphine; Retailleau, Pascal; Voituriez, Arnaud; Marinetti, Angela
• Is Part Of: ChemCatChem. Volume 5:Issue 7(2013:Jul.)
• Page Start: 2051
• Page End: 2057
• Publication Date: 2013-03-25
• Subjects: Catalysis -- Periodicals; 541.39505
• DOI: 10.1002/cctc.201200743
• Languages: English
• ISSNs: 1867-3880

Abstract

<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The enantioselective cycloisomerization of 3‐hydroxylated 1, 5‐enynes into bicyclo[3.1.0]hexanones was investigated by using cyclometalated NHC‐platinum phosphoramidite complexes as pre‐catalysts. Several new complexes were prepared. They generate cationic, electrophilic Pt^II species that efficiently promote the cycloisomerization process. Enantiomeric excesses up to 81 % were obtained in the reactions of enynes with aryl‐substituted alkyne functions (8 examples, 70–81 % <italic>ee</italic>).</p> </abstract>