Incidence and predictors of permanent pacemaker implantation following transcatheter aortic valve implantation: Analysis from the german transcatheter aortic valve interventions registry. Issue 4 (13th April 2013)

• Record Type: Journal Article
• Authors: Ledwoch, Jakob; Franke, Jennifer; Gerckens, Ulrich; Kuck, Karl‐Heinz; Linke, Axel; Nickenig, Georg; Krülls‐Münch, Jürgen; Vöhringer, Matthias; Hambrecht, Rainer; Erbel, Raimund; Richardt, Gert; Horack, Martin; Zahn, Ralf; Senges, Jochen; Sievert, Horst
• Is Part Of: Catheterization and cardiovascular interventions. Volume 82:Issue 4(2013:Oct. 01)
• Page Start: E569
• Page End: E577
• Publication Date: 2013-04-13
• Subjects: Heart -- Diseases -- Diagnosis -- Periodicals; Cardiac catheterization -- Periodicals; 616.1207572
• DOI: 10.1002/ccd.24915
• Languages: English
• ISSNs: 1522-1946

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="ccd24915-sec-0001" sec-type="section"> <title>Objectives</title> <p>To determine predictors of permanent pacemaker (PPM) implantation up to 30 days after transcatheter aortic valve implantation (TAVI) in a prospective multicenter registry.</p> </sec> <sec id="ccd24915-sec-0002" sec-type="section"> <title>Background</title> <p>Conduction disorders requiring PPM implantation are one of the most common complications seen after TAVI. Knowledge about possible predictors may help to decrease the rate of PPM implantations.</p> </sec> <sec id="ccd24915-sec-0003" sec-type="section"> <title>Methods</title> <p>In total, 1347 consecutive patients who underwent TAVI in 22 centers were prospectively enrolled in the German transcatheter aortic valve interventions registry. Both Medtronic CoreValve™ and Edwards Sapien™ valves were implanted. Patients with preprocedurally implanted PPM or implantable cardioverter defibrillator were excluded from the analysis (<italic>n</italic> = 199). Regression analysis of baseline and procedure characteristics of the remaining 1, 147 patients was performed.</p> </sec> <sec id="ccd24915-sec-0004" sec-type="section"> <title>Results</title> <p>Procedural success was achieved in 97.4% of the cases. The rate for PPM after TAVI was 33.7%. The absence of prior valve surgery, the use of Medtronic CoreValve™ prosthesis and the presence of a porcelain aorta were identified as independent predictors for PPM after TAVI. Mortality at 30 days did not differ between patients with or without PPM necessity (6.0% vs. 8.1%, respectively; HR 0.72; CI (0.45–1.16); <italic>P</italic> = 0.17).</p> </sec> <sec id="ccd24915-sec-0005" sec-type="section"> <title>Conclusions</title> <p>PPM is a common postprocedure requirement after TAVI. The absence of prior valve surgery, the implantation of Medtronic CoreValve™ prosthesis, and the presence of a porcelain aorta were independently associated with PPM after TAVI. © 2013 Wiley Periodicals, Inc.</p> </sec> </abstract>