Inside Cover: Formation of RNA Phosphodiester Bond by Histidine‐Containing Dipeptides (ChemBioChem 2/2013). Issue 2 (17th January 2013)

• Record Type: Journal Article
• Authors: Wieczorek, Rafał; Dörr, Mark; Chotera, Agata; Luisi, Pier Luigi; Monnard, Pierre‐Alain
• Is Part Of: Chembiochem. Volume 14:Issue 2(2013)
• Page Start: 166
• Page End: 166
• Publication Date: 2013-01-17
• Subjects: Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.201390001
• Languages: English
• ISSNs: 1439-4227

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>The inside cover picture shows</bold> the oligomerization of activated RNA monomers by the catalytic dipeptide Ser‐His. On <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">p. 217 ff.</ext-link>, P.‐A. Monnard et al. explain how the reaction takes place in a water/ice eutectic phase below 0 °C. This reaction environment is believed to be prebiotically plausible and likely present today on various planetary bodies like the moon Europa (background photograph: NASA, http://photojournal.jpl.nasa.gov).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1p8ft9bt" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>