Biosynthesis of the Natural Fluorophore Legioliulin from Legionella. Issue 12 (2nd July 2013)

• Record Type: Journal Article
• Authors: Ahrendt, Tilman; Miltenberger, Melissa; Haneburger, Ina; Kirchner, Ferdinand; Kronenwerth, Max; Brachmann, Alexander O.; Hilbi, Hubert; Bode, Helge B.
• Is Part Of: Chembiochem. Volume 14:Issue 12(2013)
• Page Start: 1415
• Page End: 1418
• Publication Date: 2013-07-02
• Subjects: Biochemistry -- Periodicals; Molecular biology -- Periodicals; Pharmaceutical chemistry -- Periodicals; 572
• DOI: 10.1002/cbic.201300373
• Languages: English
• ISSNs: 1439-4227

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Let it shine:</bold> The biosynthesis of the UV fluorophore legioliulin (<bold>1</bold>) from <italic>Legionella</italic> spp. was elucidated and the phenylalanine ammonium lyase LglD responsible for the formation of the starter unit cinnamic acid was biochemically characterized. Additionally, two novel derivatives differing in the starter unit have been identified by mutasynthesis experiments.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36pqvssn" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>