Drug Delivery: Multifunctional Up‐Converting Nanocomposites with Smart Polymer Brushes Gated Mesopores for Cell Imaging and Thermo/pH Dual‐Responsive Drug Controlled Release (Adv. Funct. Mater. 33/2013). (3rd September 2013)

• Record Type: Journal Article
• Authors: Zhang, Xiao; Yang, Piaoping; Dai, Yunlu; Ma, Ping'an; Li, Xuejiao; Cheng, Ziyong; Hou, Zhiyao; Kang, Xiaojiao; Li, Chunxia; Lin, Jun
• Is Part Of: Advanced functional materials. Volume 23:Number 33(2013)
• Page Start: 4062
• Page End: 4062
• Publication Date: 2013-09-03
• Subjects: Materials -- Periodicals; Chemical vapor deposition -- Periodicals; 620.11
• DOI: 10.1002/adfm.201370164
• Languages: English
• ISSNs: 1616-301X

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">On page 4067</ext-link>, Z. Cheng, J. Lin, and co‐workers report the synthesis of a multifunctional nanocomposite as an anticancer drug carrier based on a NaYF₄:Yb³⁺/Er³⁺ core and mesoporous silica shell with thermo/pH‐coupled sensitive polymer brushes grafted onto the silica surface as gate molecules. The particles can be used as fluorescent upconverters for cell imaging, and the drug release property can be promoted either by decreasing the pH to match the acidic tumor environment or by NIR laser irradiation. <boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg36gr1nx5" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>