Reverse Regioselectivity in the Palladium(II) Thiourea Catalyzed Intermolecular Pauson–Khand Reaction. Issue 1 (19th October 2012)

• Record Type: Journal Article
• Authors: Wu, Na; Deng, Lujiang; Liu, Lianzhu; Liu, Qi; Li, Chuangchuang; Yang, Zhen
• Is Part Of: Chemistry, an Asian journal. Volume 8:Issue 1(2013:Jan.)
• Page Start: 65
• Page End: 68
• Publication Date: 2012-10-19
• Subjects: Chemistry -- Periodicals; 540.5
• DOI: 10.1002/asia.201200783
• Languages: English
• ISSNs: 1861-4728

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>Which way?</bold> Palladium thiourea catalyzed Pauson–Khand reaction of norbornene with substituted alkynoates to afford selectively either α‐carboxylated adducts or β‐carboxylated adducts with the reverse regioselectivity has been demonstrated for the first time. Control of the regioselectivity in this transformation is governed by the addition of LiCl. A mechanistic interpretation to account for this observed regioselectivity is presented.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg1p9vhdbt" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>