Cover Picture: On the Way Towards Greener Transition‐Metal‐Catalyzed Processes as Quantified by E Factors (Angew. Chem. Int. Ed. 42/2013). Issue 42 (25th September 2013)

• Record Type: Journal Article
• Authors: Lipshutz, Bruce H.; Isley, Nicholas A.; Fennewald, James C.; Slack, Eric D.
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 42(2013)
• Page Start: 10911
• Page End: 10911
• Publication Date: 2013-09-25
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201308153
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>As E Factors drop</bold> it's a win‐win for chemistry and the environment. In their Minireview on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 10952 ff., </ext-link> B. H. Lipshutz and co‐workers document, by direct comparisons with transition‐metal‐catalyzed cross‐coupling reactions from pharma, just how low they can go using a commercially available designer surfactant in water as the reaction medium. As the organic solvent usage drops, E Factors can plummet by as much as an order of magnitude. Let's get organic solvents out of organic reactions, and increase sustainability.<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg3kg2m042" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>