Back Cover: Rapid, Isothermal DNA Self‐Replication Induced by a Destabilizing Lesion (Angew. Chem. Int. Ed. 40/2013). Issue 40 (20th August 2013)

• Record Type: Journal Article
• Authors: Kausar, Abu; Mitran, Catherine J.; Li, Yimeng; Gibbs‐Davis, Julianne M.
• Is Part Of: Angewandte Chemie international edition. Volume 52:Issue 40(2013)
• Page Start: 10660
• Page End: 10660
• Publication Date: 2013-08-20
• Subjects: Chemistry -- Periodicals; 540
• DOI: 10.1002/anie.201306894
• Languages: English
• ISSNs: 1433-7851

Abstract

<abstract abstract-type="graphical" xml:lang="en"> <title> <x xml:space="preserve">Abstract</x> </title> <p>Like clockwork, rapid isothermal self‐replication of oligonucleotides can be achieved using a cross‐catalytic strategy as reported by J. M. Gibbs‐Davis et al. in their Communication on <ext-link ext-link-type="doi" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">page 10577 ff.</ext-link> The presence of both a destabilizing lesion in one of the replicating fragments and concentrated DNA polymerase results in high reaction rates and are key to multiple replication cycles (Photo by Dean Albrecht).<boxed-text content-type="graphic" position="anchor" orientation="portrait"><graphic position="anchor" mimetype="image" xlink:href="ark:/27927/pgg3h9m31rm" orientation="portrait" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink" /></boxed-text></p> </abstract>