Acute peripartum twin–twin transfusion syndrome: Incidence, risk factors, placental characteristics and neonatal outcome. Issue 1 (22nd July 2013)

• Record Type: Journal Article
• Authors: Lopriore, Enrico; Holtkamp, Nanneke; Sueters, Marieke; Middeldorp, Johanna M.; Walther, Frans J.; Oepkes, Dick
• Is Part Of: Journal of obstetrics and gynaecology research. Volume 40:Issue 1(2014:Jan.)
• Page Start: 18
• Page End: 24
• Publication Date: 2013-07-22
• Subjects: Gynecology -- Periodicals; Obstetrics -- Periodicals; 618.1005
• DOI: 10.1111/jog.12114
• Languages: English
• ISSNs: 1341-8076

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="jog12114-sec-0001" sec-type="section"> <title>Aim</title> <p>The aim of this study was to examine the incidence, placental characteristics and outcome in acute peripartum twin–twin transfusion syndrome (TTTS).</p> </sec> <sec id="jog12114-sec-0002" sec-type="section"> <title>Material and Methods</title> <p>All consecutive cases of monochorionic (MC) twins admitted to our center were included in the study. We excluded cases with chronic TTTS or twin anemia polycythemia sequence. Acute peripartum TTTS was defined when the inter‐twin hemoglobin difference at birth was &gt;8 g/dL.</p> </sec> <sec id="jog12114-sec-0003" sec-type="section"> <title>Results</title> <p>A total of 241 MC twin pregnancies were included in the study. Acute peripartum TTTS was detected in six cases (2.5%, 6/241). Vaginal delivery occurred more often in the acute peripartum TTTS group compared to the control group of uncomplicated MC pregnancies, 100% (6/6) versus 57% (135/235) (<italic>P</italic> = 0.002), respectively. Acute anemia was detected only in firstborn twins. Placental angioarchitecture in acute peripartum TTTS was similar to the placentas in the control group.</p> </sec> <sec id="jog12114-sec-0004" sec-type="section"> <title>Conclusions</title> <p>The incidence of acute peripartum TTTS is low (2.5%). Birth order and mode of delivery appear to be associated with increased risk of acute peripartum TTTS.</p> </sec> </abstract>