Early postsurgical visualization of composite mesh used in ventral hernia repair by amide proton transfer MRI. Issue 1 (19th February 2013)

• Record Type: Journal Article
• Authors: Franconi, Florence; Roux, Jérome; Garric, Xavier; Lemaire, Laurent
• Is Part Of: Magnetic resonance in medicine. Volume 71:Issue 1(2014:Jan.)
• Page Start: 313
• Page End: 317
• Publication Date: 2013-02-19
• Subjects: Nuclear magnetic resonance -- Periodicals; Electron paramagnetic resonance -- Periodicals; 616.07548
• DOI: 10.1002/mrm.24666
• Languages: English
• ISSNs: 0740-3194

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="mrm24666-sec-0001" sec-type="section"> <title>Purpose</title> <p>The feasibility of noninvasive visualization of composite meshes used in ventral hernia repair by amide‐proton transfer magnetic resonance imaging (APT‐MRI) was explored.</p> </sec> <sec id="mrm24666-sec-0002" sec-type="section"> <title>Methods</title> <p>Magnetization transfer asymmetry ratio images of composite meshes were obtained in vitro and in vivo from fast‐spin echo acquisitions with frequency saturation offsets of ±3.5 ppm with respect to water frequency and no saturation. Three rats were assessed with APT‐MRI each week for 1 month after the intraperitoneal implantation of two meshes, one on each side of the incision. One mesh was coated with collagen and the other was not.</p> </sec> <sec id="mrm24666-sec-0003" sec-type="section"> <title>Results</title> <p>In vitro, meshes were delineated with APT‐MRI as a thin continuous linear hypersignal located on one side of the mesh. Unlike collagen‐free meshes, collagen‐coated meshes were easily identified in vivo with APT‐MRI during the first 3 weeks postimplantation. The composite meshes magnetization transfer asymmetry ratio (8.7 ± 2.8%) were significantly different from the muscle magnetization transfer asymmetry ratio value (−0.9 ± 1.6%). After a month, the mesh value dropped down to 1.1 ± 3.9%. Muscle and mesh magnetization transfer asymmetry ratio values were not significantly different and mesh conspicuity was no longer possible.</p> </sec> <sec id="mrm24666-sec-0004" sec-type="section"> <title>Conclusion</title> <p>The results suggest that APT‐MRI is a promising technique for noninvasive, early postsurgical visualization of composite meshes used in ventral hernia repair. <bold>Magn Reson Med 71:313–317, 2014. © 2013 Wiley Periodicals, Inc.</bold></p> </sec> </abstract>