Exercise boosts hippocampal volume by preventing early age‐related gray matter loss. Issue 2 (26th November 2013)

• Record Type: Journal Article
• Authors: Fuss, Johannes; Biedermann, Sarah V.; Falfán‐Melgoza, Claudia; Auer, Matthias K.; Zheng, Lei; Steinle, Jörg; Hörner, Felix; Sartorius, Alexander; Ende, Gabriele; Weber‐Fahr, Wolfgang; Gass, Peter
• Is Part Of: Hippocampus. Volume 24:Issue 2(2014:Feb.)
• Page Start: 131
• Page End: 134
• Publication Date: 2013-11-26
• Subjects: Hippocampus (Brain) -- Periodicals; 612.825
• DOI: 10.1002/hipo.22227
• Languages: English
• ISSNs: 1050-9631

Abstract

<abstract abstract-type="main"> <title>ABSTRACT</title> <p>Recently, a larger hippocampus was found in exercising mice and men. Here we studied the morphological underpinnings in wheel running mice by longitudinal magnetic resonance imaging. Voxel‐based morphometry revealed that running increases hippocampal volume by inhibiting an early age‐related gray matter loss. Disruption of neurogenesis‐related neuroplasticity by focalized irradiation is sufficient to block positive effects of exercise on macroscopic brain morphology. © 2013 Wiley Periodicals, Inc.</p> </abstract>