Long‐term results of endoscopic resection for type I gastric neuroendocrine tumors. Issue 2 (25th October 2013)

• Record Type: Journal Article
• Authors: Uygun, Ahmet; Kadayifci, Abdurrahman; Polat, Zulfikar; Yilmaz, Kemalettin; Gunal, Armagan; Demir, Hakan; Bagci, Sait
• Is Part Of: Journal of surgical oncology. Volume 109:Issue 2(2014:Feb. 01)
• Page Start: 71
• Page End: 74
• Publication Date: 2013-10-25
• Subjects: Cancer -- Surgery -- Periodicals; Neoplasms -- Periodicals; 616
• DOI: 10.1002/jso.23477
• Languages: English
• ISSNs: 0022-4790

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jso23477-sec-0001" sec-type="section"> <title>Background</title> <p>A number of different therapies, including endoscopic resection, have been suggested for the treatment of Type 1 gastric neuroendocrine tumors (NETs). The current study aimed to determine the long‐term efficacy of endoscopic resection for Type 1 gastric NETs.</p> </sec> <sec id="jso23477-sec-0002" sec-type="section"> <title>Methods</title> <p>Twenty‐two patients (from 1999 to 2012) with Type 1 gastric NETs were included in the study. All patients were treated with endoscopic resection and received regular followed‐up appointments at a tertiary referral center.</p> </sec> <sec id="jso23477-sec-0003" sec-type="section"> <title>Results</title> <p>All patients were initially diagnosed with hypergastrinemia, atrophic gastritis and intestinal metaplasia. Polyps' diameters were >1 cm in 4 patients, and between 0.5 and 1 cm in 18 patients. All detectable lesions were successfully resected. One patient required surgery due to gastric perforation during endoscopic mucosal resection. Recurrence was detected in four patients (18%) and endoscopic resection was performed again. Local or distant metastasis was not observed in any patient during follow‐up. Median follow‐up time was 7 years, with a maximum of 14 years. Seventeen patients (78%) completed a 5‐year follow‐up period, and overall disease‐free survival rate was 100%.</p> </sec> <sec id="jso23477-sec-0004" sec-type="section"> <title>Conclusions</title> <p>Long‐term follow‐ups with 22 patients suggest that endoscopic resection of Type 1 gastric NETs is a safe and effective treatment option with a relatively low recurrence rate. <italic>J. Surg. Oncol. 2014 109:71–74</italic>. © 2013 Wiley Periodicals, Inc.</p> </sec> </abstract>