3 Tesla 1H MR spectroscopy of hip bone marrow in a healthy population, assessment of normal fat content values and influence of age and sex. Issue 2 (15th May 2013)

• Record Type: Journal Article
• Authors: Pansini, Vittorio; Monnet, Aurélien; Salleron, Julia; Hardouin, Pierre; Cortet, Bernard; Cotten, Anne
• Is Part Of: Journal of magnetic resonance imaging. Volume 39:Issue 2(2014)
• Page Start: 369
• Page End: 376
• Publication Date: 2013-05-15
• Subjects: Magnetic resonance imaging -- Periodicals; 616
• DOI: 10.1002/jmri.24176
• Languages: English
• ISSNs: 1053-1807

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="jmri24176-sec-0001" sec-type="section"> <title>Purpose</title> <p>To evaluate in a healthy population normal spectroscopic fat content (FC) values of the hip bone marrow and to assess the influence of age and sex on bone marrow conversion.</p> </sec> <sec id="jmri24176-sec-0002" sec-type="section"> <title>Materials and Methods</title> <p>Eighty volunteers (40 men; 40 women; ages: 20–60 years; divided into four consecutive groups) underwent acetabulum, femoral head, femoral neck, greater trochanter, and diaphysis localized <sup>1</sup>H MR spectroscopy. FC values of each anatomical site were obtained according to the following formula: Fat content = CH<sub>2</sub>/(CH<sub>2</sub> + Water)*100. To assess bone marrow conversion, a spectroscopic conversion index (SCI) was calculated as FC neck/FC greater trochanter.</p> </sec> <sec id="jmri24176-sec-0003" sec-type="section"> <title>Results</title> <p>FC values showed a gradient as follows: greater trochanter > femoral head > femoral neck > diaphysis > acetabulum in every age group both in men and in women. SCI increased with age both in men and women, showing lower values in women for every age group.</p> </sec> <sec id="jmri24176-sec-0004" sec-type="section"> <title>Conclusion</title> <p>We obtained normal spectroscopic FC values from different areas of the hip, according to age and sex. These values may be used as reference values to evaluate, by the means of <sup>1</sup>H MR spectroscopy, pathological conditions affecting hip bone marrow. <bold>J. Magn. Reson. Imaging 2014;39:369–376</bold>. © <bold>2013 Wiley Periodicals, Inc</bold>.</p> </sec> </abstract>