How plausible is a link between HSV-1 infection and Alzheimer's disease?. Issue 3 (March 2014)

• Record Type: Journal Article
• Authors: Agostini, Simone; Clerici, Mario; Mancuso, Roberta
• Is Part Of: Expert review of anti-infective therapy. Volume 12:Issue 3(2014)
• Page Start: 275
• Page End: 278
• Publication Date: 2014-03
• Subjects: Anti-infective agents -- Research -- Periodicals; 616.90461
• DOI: 10.1586/14787210.2014.887442
• Languages: English
• ISSNs: 1478-7210

Abstract

<abstract> <title> <x xml:space="preserve">Abstract</x> </title> <p>Alzheimer's disease is a leading cause of dementia with a multifactorial and still barely understood etiology. A growing body of epidemiologic and experimental data support a role for infectious agents in this process; herpes simplex virus 1 (HSV-1), in particular, is a strong suspect. We briefly summarize the data pointing at a pathogenic role for HSV-1 in the development of Alzheimer's disease and review results indicating that antiviral might be beneficial in the therapy of this condition.</p> </abstract>