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ChemInform Abstract: Chemical, Pharmacological, and in vitro Metabolic Stability Studies on Enantiomerically Pure RC‐33 Compounds: Promising Neuroprotective Agents Acting as σ1 Receptor Agonists. Issue 4 (28th January 2014)
Record Type:
Journal Article
Title:
ChemInform Abstract: Chemical, Pharmacological, and in vitro Metabolic Stability Studies on Enantiomerically Pure RC‐33 Compounds: Promising Neuroprotective Agents Acting as σ1 Receptor Agonists. Issue 4 (28th January 2014)
Main Title:
ChemInform Abstract: Chemical, Pharmacological, and in vitro Metabolic Stability Studies on Enantiomerically Pure RC‐33 Compounds: Promising Neuroprotective Agents Acting as σ1 Receptor Agonists.
<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>Both RC‐33 enantiomers (III) show similar affinities for the σ<sub>1</sub> receptor, but the (R)‐RC‐33 exhibits higher in vitro hepatic metabolic stability in the presence of NADPH.</p> </abstract>