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ChemInform Abstract: Synthesis, G‐Quadruplex Stabilization, Docking Studies, and Effect on Cancer Cells of Indolo[3, 2‐b]quinolines with One, Two, or Three Basic Side Chains. Issue 8 (25th February 2014)
Record Type:
Journal Article
Title:
ChemInform Abstract: Synthesis, G‐Quadruplex Stabilization, Docking Studies, and Effect on Cancer Cells of Indolo[3, 2‐b]quinolines with One, Two, or Three Basic Side Chains. Issue 8 (25th February 2014)
Main Title:
ChemInform Abstract: Synthesis, G‐Quadruplex Stabilization, Docking Studies, and Effect on Cancer Cells of Indolo[3, 2‐b]quinolines with One, Two, or Three Basic Side Chains.
<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The synthesized compounds, especially compounds (IIIb) and (IVb) show high G‐Quadruplex (G4) thermal stabilization over duplex DNA and selectivity for the HCT116 cancer cell line over primary rat hepatocytes.</p> </abstract>