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ChemInform Abstract: β‐Lactam‐Synthon‐Interceded Synthesis of Isatin—Imidazolidine‐2‐thione Conjugates with Structural Validation Using Molecular Dynamic Simulations and Cytotoxic Evaluation. Issue 5 (4th February 2014)
Record Type:
Journal Article
Title:
ChemInform Abstract: β‐Lactam‐Synthon‐Interceded Synthesis of Isatin—Imidazolidine‐2‐thione Conjugates with Structural Validation Using Molecular Dynamic Simulations and Cytotoxic Evaluation. Issue 5 (4th February 2014)
Main Title:
ChemInform Abstract: β‐Lactam‐Synthon‐Interceded Synthesis of Isatin—Imidazolidine‐2‐thione Conjugates with Structural Validation Using Molecular Dynamic Simulations and Cytotoxic Evaluation.
<abstract abstract-type="main" xml:lang="en"> <title>Abstract</title> <p>The anion derived from isatins (I) reacts with isocyanates (II) to form imidazolidine‐2‐thiones (III), some of which show significant cytotoxic activity against the oesophageal cancer cell line WHCO1.</p> </abstract>