Acute kidney injury due to tubular intraluminal monoclonal light chain crystals mimicking acute pyelonephritis. (March 2014)

• Record Type: Journal Article
• Authors: Haider, Mumnoon; Salvatore, Steven P.; Kaplan, Joshua; Seshan, Surya V.
• Is Part Of: Renal failure. Volume 36:Number 2(2014)
• Page Start: 300
• Page End: 305
• Publication Date: 2014-03
• Subjects: Chronic renal failure -- Periodicals; Acute renal failure -- Periodicals; Uremia -- Periodicals; 616.614005
• DOI: 10.3109/0886022X.2013.844643
• Languages: English
• ISSNs: 0886-022X

Abstract

<abstract> <title>Abstract</title> <p>Tubular intraluminal inflammatory cells may be seen in kidney biopsies of patients with pyelonephritis, cell-mediated transplant rejection, autoimmune tubulointerstitial nephritis, allergic reactions, or in association with monoclonal light chain casts. When casts in a native kidney are primarily composed of granulocytes, the cause is most commonly acute pyelonephritis due to an ascending bacterial urinary tract infection. We report a 57-year-old man with acute kidney injury and an intense intraluminal neutrophil response to monoclonal lambda light chain crystal containing casts.</p> </abstract>