D-Psicose increases energy expenditure and decreases body fat accumulation in rats fed a high-sucrose diet. (March 2014)

• Record Type: Journal Article
• Authors: Ochiai, Masaru; Onishi, Kana; Yamada, Takako; Iida, Tetsuo; Matsuo, Tatsuhiro
• Is Part Of: International journal of food sciences and nutrition. Volume 65:Number 2(2014)
• Page Start: 245
• Page End: 250
• Publication Date: 2014-03
• Subjects: Food -- Analysis -- Periodicals; Nutrition -- Periodicals; 641.3
• DOI: 10.3109/09637486.2013.845653
• Languages: English
• ISSNs: 0963-7486

Abstract

<abstract> <title>Abstract</title> <p>We investigated the anti-obesity effects of <sc>d</sc>-psicose by increasing energy expenditure in rats pair-fed the high-sucrose diet (HSD). Wistar rats were divided into two dietary groups: HSD containing 5% cellulose (C) and 5% <sc>d</sc>-psicose (P). The C dietary group was further subdivided into two groups: rats fed the C diet ad libitum (C-AD) and pair-fed the C diet along with those in the P group (C-PF). Resting energy expenditure during darkness and lipoprotein lipase activity in the soleus muscle were significantly higher in the P group than in the C-PF group. Serum levels of glucose, leptin and adiponectin; glucose-6-phosphate dehydrogenase activities in the liver and perirenal adipose tissue; and body fat accumulation were all significantly lower in the P group than in the C-PF group. The anti-obesity effects of D-psicose could be induced not only by suppressing lipogenic enzyme activity but also by increasing EE in rats.</p> </abstract>