Analysis of cerebral toxoplasmosis in a series of 170 allogeneic hematopoietic stem cell transplant patients. Issue 6 (18th September 2013)

• Record Type: Journal Article
• Authors: Hakko, E.; Ozkan, H.A.; Karaman, K.; Gulbas, Z.
• Is Part Of: Transplant infectious disease. Volume 15:Issue 6(2013)
• Page Start: 575
• Page End: 580
• Publication Date: 2013-09-18
• Subjects: Transplantation of organs, tissues, etc -- Complications -- Periodicals; Communicable diseases -- Periodicals; Infection -- Periodicals; 617.01
• DOI: 10.1111/tid.12138
• Languages: English
• ISSNs: 1398-2273

Abstract

<abstract abstract-type="main" id="tid12138-abs-0001"> <title>Abstract</title> <sec id="tid12138-sec-0001" sec-type="section"> <title>Introduction</title> <p>Cerebral toxoplasmosis is a rare but fatal complication in hematopoietic stem cell transplant patients, which mostly is caused by reactivation of latent disease.</p> </sec> <sec id="tid12138-sec-0002" sec-type="section"> <title>Methods</title> <p>In this study, we report an analysis of cerebral toxoplasmosis in a series of 170 allogeneic stem cell transplant patients during a 30‐month period at our institution.</p> </sec> <sec id="tid12138-sec-0003" sec-type="section"> <title>Results</title> <p>Among these allogeneic stem cell transplant patients, 5 were diagnosed with cerebral toxoplasmosis by brain magnetic resonance imaging and polymerase chain reaction of <italic>Toxoplasma gondii </italic>DNA. The incidence of cerebral toxoplasmosis was found to be 2.94%.</p> </sec> <sec id="tid12138-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Mortality rate is known to be very high in cerebral toxoplasmosis; therefore, it is life saving to diagnose the disease in the early stages and start treatment promptly, especially in high‐endemic countries like Turkey.</p> </sec> </abstract>