High‐frequency (20–50 MHz) ultrasonography of pseudoxanthoma elasticum skin lesions. (December 2013)

• Record Type: Journal Article
• Authors: Guérin‐Moreau, M.; Leftheriotis, G.; Le, Y.; Etienne, M.; Amode, R.; Hamel, J.F.; Croué, A.; Le, O.; Machet, L.; Martin, L.
• Is Part Of: British journal of dermatology. Volume 169:Number 6(2013:Dec.)
• Page Start: 1233
• Page End: 1239
• Publication Date: 2013-12
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5
• DOI: 10.1111/bjd.12545
• Languages: English
• ISSNs: 0007-0963

Abstract

<abstract abstract-type="short" xml:lang="en" id="bjd12425-abs-0002"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>What's already known about this topic?</bold> </p> <p> <list id="bjd12545-list-0001" list-type="bullet"> <list-item> <p>Typical pseudoxanthoma elasticum (PXE) skin changes are yellowish papules and are associated with unique elastic fibre fragmentation and calcification on skin biopsy.</p> </list-item> <list-item> <p>High‐frequency ultrasonography (HFUS) features of cutaneous PXE have not been reported previously.</p> </list-item> </list> </p> <p> <bold>What does this study add?</bold> </p> <p> <list id="bjd12545-list-0002" list-type="bullet"> <list-item> <p>Noninvasive HFUS examination of the skin of patients with PXE revealed unique echostructure characteristics with oval homogeneous hypoechogenic areas in the mid‐dermis.</p> </list-item> <list-item> <p>These features may be useful for diagnosis of PXE in ambiguous cases and may aid the choice of skin site for biopsy in patients with subtle or no clinical changes.</p> </list-item> <list-item> <p>The hypoechogenic areas were consistent with the presence of localized hydration due to deposits of glycosaminoglycans.</p> </list-item> </list> </p> </abstract>