CT‐guided core biopsy of malignant lung lesions: How many needle passes are needed?. Issue 6 (1st April 2013)

• Record Type: Journal Article
• Authors: Lim, Chaehun; Lee, Kyo Young; Kim, Young Kyoon; Ko, Jeong Min; Han, Dae Hee
• Is Part Of: Journal of medical imaging and radiation oncology. Volume 57:Issue 6(2013:Dec.)
• Page Start: 652
• Page End: 656
• Publication Date: 2013-04-01
• Subjects: Radiology, Medical -- Periodicals; Radiology, Medical -- Australasia -- Periodicals; 616.0757
• DOI: 10.1111/1754-9485.12054
• Languages: English
• ISSNs: 1754-9477

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="jmiro12054-sec-0001" sec-type="section"> <title>Aim</title> <p>The study aims to determine the number of needle pass in the CT‐guided core needle biopsy (CNB) in making a diagnosis of pulmonary malignancy.</p> </sec> <sec id="jmiro12054-sec-0002" sec-type="section"> <title>Materials and methods</title> <p>A total of 434 CNB records were retrospectively reviewed. The specimen obtained from each needle pass was put in a formalin container and then labelled for separate histopathological reporting. The patients were divided into five groups according to the total number of needle passes (<italic>n</italic> = 1, <italic>n</italic> = 2, <italic>n</italic> = 3, <italic>n</italic> = 4 and <italic>n</italic> ≥ 5). In each of the groups 2–4, it was analysed how many needle passes are required before a plateau in diagnostic yield is achieved.</p> </sec> <sec id="jmiro12054-sec-0003" sec-type="section"> <title>Results</title> <p>CNB produced 283 true‐positive and 23 false‐negative diagnosis of malignancy. Cumulative sensitivity significantly (<italic>P</italic> &lt; 0.05) increased between the first and second as well as the second and the third (if done) needle passes, but not between the third and fourth ones.</p> </sec> <sec id="jmiro12054-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Three coaxial needle passes might be optimal in the diagnosis of lung malignancy.</p> </sec> </abstract>