A Simple and Environmentally Benign Nitration of Pyrazoles by Impregnated Bismuth Nitrate. (9th September 2013)

• Record Type: Journal Article
• Authors: Ravi, P.; Gore, Girish M.; Tewari, Surya P.; Sikder, Arun K.
• Is Part Of: Journal of heterocyclic chemistry. Volume 50:Number 6(2013:Nov.)
• Page Start: 1322
• Page End: 1327
• Publication Date: 2013-09-09
• Subjects: Heterocyclic compounds -- Periodicals; 547.59
• DOI: 10.1002/jhet.1093
• Languages: English
• ISSNs: 0022-152X

Abstract

<abstract abstract-type="main" id="jhet1093-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p id="jhet1093-para-0002">We report herein a facile, rapid, and environmentally friendly synthesis of nitropyrazoles in good yields using silica‐bismuth nitrate and silica‐sulfuric acid‐bismuth nitrate at room temperature for the first time. The relatively non‐toxic nature, ease of handling, easy availability, and low cost make the present procedure attractive for the <named-content id="d482e764" content-type="reactionType" xlink:type="simple" xmlns:xlink="http://www.w3.org/1999/xlink">nitration</named-content> of a wide variety of diazoles in the drug and pharmaceutical industries.</p> </abstract>