Colonic decompression and direct intraluminal medical therapy for Clostridium difficile‐associated megacolon using a tube placed endoscopically in the proximal colon. (February 2014)

• Record Type: Journal Article
• Authors: Causey, M. W.; Walker, A.; Cummings, M.; Johnson, E. K.; Maykel, J. A.; Steele, S.
• Is Part Of: Colorectal disease. Volume 16:Number 2(2014)
• Page Start: O71
• Page End: O74
• Publication Date: 2014-02
• Subjects: Colon (Anatomy) -- Diseases -- Periodicals; Rectum -- Diseases -- Periodicals; 616.34
• DOI: 10.1111/codi.12463
• Languages: English
• ISSNs: 1462-8910

Abstract

<abstract abstract-type="main" id="codi12463-abs-0001"> <title>Abstract</title> <sec id="codi12463-sec-0001" sec-type="section"> <title>Aim</title> <p>Urgent colectomy for severe <italic>Clostridium difficile</italic> infection can be associated with increased morbidity and mortality. We aimed to use endoscopic methods for treatment.</p> </sec> <sec id="codi12463-sec-0002" sec-type="section"> <title>Method</title> <p>We describe a technique of placing an intracolonic tube facilitating decompression and direct delivery of vancomycin to the proximal colon along with enemas on a regular and frequent basis that may not be possible with vancomycin enemas alone.</p> </sec> <sec id="codi12463-sec-0003" sec-type="section"> <title>Results</title> <p>Successful resolution of the <italic>C. difficile</italic> infection and avoidance of surgery.</p> </sec> <sec id="codi12463-sec-0004" sec-type="section"> <title>Conclusion</title> <p>While further long‐term evaluation is required, our initial results have shown it to be effective in treating select patients with recalcitrant <italic>Clostridium difficile</italic>‐associated megacolon.</p> </sec> </abstract>