Uterine myomas treated with microwave ablation: The agreement between ablation volumes obtained from contrast-enhanced sonography and enhanced MRI. (February 2014)

• Record Type: Journal Article
• Authors: Lei, Feng; Jing, Zhang; Bo, Wen; Dongmei, Hu; Zhencai, Li; Xue, Jiang; Fang, Wang; Hongyu, Zhou; Jintao, Ren
• Is Part Of: International journal of hyperthermia. Volume 30:Number 1(2014)
• Page Start: 11
• Page End: 18
• Publication Date: 2014-02
• Subjects: Thermotherapy -- Periodicals; 615.832
• DOI: 10.3109/02656736.2013.853107
• Languages: English
• ISSNs: 0265-6736

Abstract

<abstract> <title>Abstract</title> <p> <italic>Purpose:</italic> This study explores the agreement between ablated uterine myoma volumes obtained from contrast-enhanced sonography and enhanced magnetic resonance imaging (MRI) after microwave ablation therapy. <italic>Materials and methods:</italic> Twenty uterine myomas in 18 patients (average size: 5.56 ± 1.26 cm) were successfully treated by microwave ablation. Contrast-enhanced sonography and enhanced MRI were performed within 7 days after the treatment. The ablation range of uterine myomas was observed and the ablation volume was calculated. By using the intraclass correlation coefficient (ICC) and Bland-Altman regression analysis, the agreement between ablated uterine myoma volumes obtained from contrast-enhanced sonography and enhanced MRI after microwave ablation therapy was analysed. <italic>Results:</italic> The ablated volume ranged from 13.66 to 135.27 cm<sup>3</sup> after ablation, and the mean volume was 66.59 ± 35.71 cm<sup>3</sup> by using contrast-enhanced sonography. Respectively, the ablated volume ranged from 10.88 to 137.83 cm<sup>3</sup>, and the mean volume was 66.81 ± 35.45 cm<sup>3</sup> by using enhanced MRI. The limits of agreement between the two methods were (−10.83 cm<sup>3</sup>, 8.39 cm<sup>3</sup>), ICC was 0.991 (<italic>F</italic> = 209.61, <italic>P</italic> < 0.05), and 95% confidence interval is (0.976, 0.996). The results revealed a good agreement between the two examination methods of contrast-enhanced sonography and enhanced MRI. <italic>Conclusions:</italic> Contrast-enhanced sonography and enhanced MRI can be used interchangeably in observing the ablation range of uterine myomas treated with microwave ablation. Contrast-enhanced sonography can be used as a preferred non-invasive examination and for follow-up. Meanwhile, enhanced MRI can be used to comprehensively determine the relationships among uterine myomas, the entire uterus, and surrounding tissues.</p> </abstract>