Evaluation of Erytra® fully automated analyser for Routine Use in Transfusion Laboratory. Issue 1 (5th November 2013)

• Record Type: Journal Article
• Authors: Chang, C.; Brown, M.; Davies, L.; Pointon, L.; Brown, R.; Barker, D.
• Is Part Of: Transfusion medicine. Volume 24:Issue 1(2014)
• Page Start: 33
• Page End: 38
• Publication Date: 2013-11-05
• Subjects: Blood -- Transfusion -- Periodicals; 615.39
• DOI: 10.1111/tme.12073
• Languages: English
• ISSNs: 0958-7578

Abstract

<abstract abstract-type="main" id="tme12073-abs-0001"> <title>SUMMARY</title> <sec id="tme12073-sec-0001" sec-type="section"> <title>Objective</title> <p id="tme12073-para-0001">To evaluate efficiency and performance of Erytra® analyser in comparison to the reference platform of the NBT immunohaematology laboratory (Bio‐Rad ID‐System).</p> </sec> <sec id="tme12073-sec-0002" sec-type="section"> <title>Background</title> <p id="tme12073-para-0002">Moving to automation or semi‐automation is a major focus of transfusion centres. The Erytra® (Grifols) is a new fully automated walk‐away analyser with high volume processing capacity for pre‐transfusion testing, designed to be used with the unique 8‐column DG Gel® cards.</p> </sec> <sec id="tme12073-sec-0003" sec-type="section"> <title>Study Design and Methods</title> <p id="tme12073-para-0003">A total of 2201 immunohaematological tests (1041 ABO/D grouping, 1041 antibody screening, 51 antibody identification, 45 newborns (ABO/D and DAT) and 23 crossmatches were performed on 1160 donor/patient whole blood samples. Erytra®'s performance was assessed by means of a stress test replicating the routine work of a hospital laboratory.</p> </sec> <sec id="tme12073-sec-0004" sec-type="section"> <title>Results</title> <p id="tme12073-para-0004">Concordant results between the Erytra® and the reference method were obtained in 2195 (99·73 %) of the tests. There were only three discrepancies out of 6246 reactions (0·05%) in ABO/D grouping, all in the reverse group which did not mislead to group identification. Of the 1041 samples screened for antibody presence, Erytra® detected all the relevant antibodies [9 not detected weak prophylactic anti‐D were determined to be clinically nonsignificant (<0·1 IU mL<sup>−1</sup>)] while Bio‐Rad ID‐System missed one anti‐e and one anti‐Jk<sup>a</sup>. Concordance for D grouping, crossmatching and newborns was 100%. Results of the simulated stress test exercise highlighted the capacity of Erytra® for absorbing into 4 h workloads equivalent to 24 h of routine.</p> </sec> <sec id="tme12073-sec-0005" sec-type="section"> <title>Conclusions</title> <p id="tme12073-para-0005">Grifols' Erytra® analyser showed reliable high sensitivity, velocity and capacity to cope with high workload in the immunohaematology laboratory routine.</p> </sec> </abstract>