Inflammatory myofibroblastic tumour in the nasal cavity of a dog. (9th October 2013)

• Record Type: Journal Article
• Authors: Swinbourne, F.; Kulendra, E.; Smith, K.; Leo, C.; Ter Haar, G.
• Is Part Of: Journal of small animal practice. Volume 55:Number 2(2014:Feb.)
• Page Start: 121
• Page End: 124
• Publication Date: 2013-10-09
• Subjects: Veterinary medicine -- Periodicals; Veterinary Medicine -- Periodicals; 636.089
• DOI: 10.1111/jsap.12140
• Languages: English
• ISSNs: 0022-4510

Abstract

<abstract abstract-type="main" id="jsap12140-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <p id="jsap12140-para-0001"> <bold>A 4·5‐year‐old, female neutered Leonberger was presented with a 2‐month history of sneezing, nasal discharge and epistaxis. A presumptive diagnosis of nasal aspergillosis was made based on a suspected (fungal) granuloma on rhinoscopic examination and fungal hyphae on cytological examination. A poor response to targeted therapy was observed and computed tomography 16 months after initial presentation revealed a progressive, locally invasive mass lesion. Histopathological and immunohistochemical analysis of deep surgical biopsies revealed a spindle cell population and a plasma cell rich inflammatory infiltrate, with diffuse expression of vimentin, supporting a diagnosis of inflammatory myofibroblastic tumour. Complete resolution of the nasal discharge and reduced sneezing frequency was reported 9 months post‐surgical debridement via rhinotomy. To the authors' knowledge, this is the first report of IMT in the nasal cavity of a dog. IMT should be considered when presented with a nasal mass lesion, particularly if histopathological features and clinical course are inconsistent.</bold> </p> </abstract>