Durable HIV RNA resuppression after virologic failure while remaining on a first‐line regimen: a cohort study. Issue 2 (3rd December 2013)

• Record Type: Journal Article
• Authors: Hoffmann, Christopher J.; Charalambous, Salome; Grant, Alison D.; Morris, Lynn; Churchyard, Gavin J.; Chaisson, Richard E.
• Is Part Of: Tropical medicine & international health. Volume 19:Issue 2(2014:Feb.)
• Page Start: 236
• Page End: 239
• Publication Date: 2013-12-03
• Subjects: Tropical medicine -- Periodicals; Public health -- Periodicals; 616.988
• DOI: 10.1111/tmi.12237
• Languages: English
• ISSNs: 1360-2276

Abstract

<abstract abstract-type="main" id="tmi12237-abs-0001"> <title>Summary</title> <p>Adherence interventions are a recommended strategy to salvage failing antiretroviral therapy without regimen change. We assessed the durability of resuppression when using this approach. Of 300 patients who resuppressed on the same regimen (41% of all those with virologic failure), 148 (45%) remained suppressed during follow‐up for a median of 2.4 years (interquartile range [IQR]: 1.1, 4.0). Resuppression can be durable following viraemia without a switch in antiretroviral therapy regimen.</p> </abstract>