Voiding Dysfunction in Spinocerebellar Ataxia Type 31. Issue 1 (6th May 2013)

• Record Type: Journal Article
• Authors: SUGIYAMA, Megumi; SAKAKIBARA, Ryuji; TATENO, Fuyuki; YANO, Masashi; TAKAHASHI, Osamu; KISHI, Masahiko; TSUYUSAKI, Yohei; YAMAMOTO, Tatsuya; UCHIYAMA, Tomoyuki; YAMANISHI, Tomonori; YAMAGUCHI, Chiharu; NOMURA, Fumio
• Is Part Of: LUTS. Volume 6:Issue 1(2014)
• Page Start: 64
• Page End: 67
• Publication Date: 2013-05-06
• Subjects: Urology -- Periodicals; Urologic Diseases -- Periodicals; Urinary Tract Physiological Phenomena -- Periodicals; 616.62
• DOI: 10.1111/luts.12021
• Languages: English
• ISSNs: 1757-5664

Abstract

<abstract abstract-type="main"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="luts12021-sec-0100" sec-type="section"> <title>Objective</title> <p>To describe a case of SCA31 who presented with possible neurogenic voiding dysfunction.</p> </sec> <sec id="luts12021-sec-0101" sec-type="section"> <title>Methods</title> <p>A case report.</p> </sec> <sec id="luts12021-sec-0102" sec-type="section"> <title>Results</title> <p>A 73‐year‐old man with a 5‐year history of cerebellar ataxia developed partial urinary retention. His father and a sister had cerebellar ataxia. Brain magnetic resonance imaging revealed cerebellar atrophy, and gene analysis revealed TGGAA repeat prolongation, and he was diagnosed with spinocerebellar ataxia 31. Urodynamics revealed normal bladder filling but a slightly weak detrusor and a post‐void residual urine volume of 130 mL, whereas his prostate volume was normal (26 mL). External sphincter electromyography revealed neurogenic change in the motor unit potentials. In order to lessen the post‐void residual, hewas started on 15mg/day pilocarpine with benefit. The weak detrusor and sphincter electromyography abnormality indicated involvement of the sacral spinal cord in this disorder.</p> </sec> <sec id="luts12021-sec-0103" sec-type="section"> <title>Conclusion</title> <p>Neurogenic urinary retention in SCA31 can be listed in the clinical differential diagnosis of cerebellar ataxia. However, possible outflow obstruction in men should always be explored.</p> </sec> </abstract>