Chromosome 9p21 primary open‐angle glaucoma susceptibility locus: a review. (30th October 2013)

• Record Type: Journal Article
• Authors: Ng, Soo Khai; Casson, Robert J; Burdon, Kathryn P; Craig, Jamie E
• Is Part Of: Clinical & experimental ophthalmology. Volume 42:Number 1(2014)
• Page Start: 25
• Page End: 32
• Publication Date: 2013-10-30
• Subjects: Ophthalmology -- Periodicals; 617.7
• DOI: 10.1111/ceo.12234
• Languages: English
• ISSNs: 1442-6404

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <p>Primary open‐angle glaucoma (POAG) is a genetically complex disease. Genome‐wide association study (GWAS) is a particularly useful tool in the search for genetic contributions to glaucoma. Recently, chromosome 9p21 has become a major focus of research endeavour, with multiple genome‐wide association studies suggesting associations to POAG. Herein, we provide a review of the chromosome 9p21 susceptibility locus as a risk factor for POAG.</p> </abstract>