Blood microvessel density, lymphatic microvessel density and lymphatic invasion in predicting melanoma metastases: systematic review and meta‐analysis. (January 2014)

• Record Type: Journal Article
• Authors: Pastushenko, I.; Vermeulen, P.B.; Carapeto, F.J.; Van den Eynden, G.; Rutten, A.; Ara, M.; Dirix, L.Y.; Van Laere, S.
• Is Part Of: British journal of dermatology. Volume 170:Number 1(2014:Jan.)
• Page Start: 66
• Page End: 77
• Publication Date: 2014-01
• Subjects: Dermatology -- Periodicals; Skin -- Diseases -- Periodicals; 616.5
• DOI: 10.1111/bjd.12688
• Languages: English
• ISSNs: 0007-0963

Abstract

<abstract abstract-type="short" xml:lang="en" id="bjd12688-abs-0002"> <title> <x xml:space="preserve">Abstract</x> </title> <p> <bold>What's already known about this topic?</bold> </p> <p> <list id="bjd12688-list-0001" list-type="bullet"> <list-item> <p>Both angiogenesis and lymphangiogenesis have been recognized as crucial processes in tumour growth and metastasis development.</p> </list-item> <list-item> <p>In the last two decades, large numbers of studies evaluating microvessel and lymphatic vessel density in melanoma have been published, many of them reporting contradictory results.</p> </list-item> </list> </p> <p> <bold>What does this study add?</bold> </p> <p> <list id="bjd12688-list-0002" list-type="bullet"> <list-item> <p>We performed a systematic review of all published data, followed by meta‐analysis, permitting a global evaluation of the existing evidence on the prognostic value of these parameters in melanoma.</p> </list-item> </list> </p> </abstract>