Postnatal nutrition in extremely low birth weight infants and its impact on growth until the age of 6 years. (3rd December 2013)

• Record Type: Journal Article
• Authors: Peiler, Annika; Woelfle, Joachim; Stutte, Sonja; Schreiner, Felix; Bartmann, Peter; Gohlke, Bettina
• Is Part Of: Acta pædiatrica. Volume 103:Number 2(2014:Feb.)
• Page Start: e61
• Page End: e68
• Publication Date: 2013-12-03
• Subjects: Pediatrics -- Periodicals; Pediatrics; 618.92
• DOI: 10.1111/apa.12469
• Languages: English
• ISSNs: 0803-5253

Abstract

<abstract abstract-type="main" id="apa12469-abs-0001"> <title>Abstract</title> <sec id="apa12469-sec-0001" sec-type="section"> <title>Aim</title> <p>To examine the impact of postnatal nutrition on long‐term growth in extremely low birth weight infants.</p> </sec> <sec id="apa12469-sec-0002" sec-type="section"> <title>Method</title> <p>Retrospective analysis of postnatal nutrition and observational study of growth in 52 ELBW infants until the age of six.</p> </sec> <sec id="apa12469-sec-0003" sec-type="section"> <title>Results</title> <p>Changes (Δ) in weight and length standard deviation scores (SDS) between birth to term correlated with protein intake (r<sub>w </sub>= 0.36; p = 0.009; r<sub>L </sub>= 0.35; p = 0.01), whereas ΔHC correlated with lipid intake (r<sub>HC </sub>= 0.38; p = 0.005). Analysis of various intervals (0–2, 3–5, 6–8 and 9–11 weeks) only showed significant impact on growth for energy (r = 0.3; p < 0.05) and lipids (r = 0.23; p < 0.05) at 6–8 weeks. No significant correlations were found between postnatal nutritional parameters and long‐term growth. However, postnatal growth restraint was negatively associated with length SDS (r = −0.34; p = 0.015) and body mass index SDS (r = −0.34; p = 0.018) at the age of six. Infants with postnatal growth restraint (n = 25) caught up more in length (+1.78 SDS) than in weight (+0.43 SDS), whereas small for gestational age infants (n = 8) caught up more in weight (+1.35 SDS) than in length (+1.07 SDS). This difference remained significant at the age of six.</p> </sec> <sec id="apa12469-sec-0004" sec-type="section"> <title>Conclusion</title> <p>Although no direct association between postnatal nutrition and long‐term growth was found, weight at discharge was a strong predictor for long‐term growth.</p> </sec> </abstract>