Presentation of Suspected Pediatric Uveitis. (January 2014)

• Record Type: Journal Article
• Authors: Saeed, Muhammad Usman; Raza, Syed Hamid; Goyal, Sudeshna; Cleary, Gavin; Newman, William David; Chandna, Arvind
• Is Part Of: Seminars in ophthalmology. Volume 29:Number 1(2014)
• Page Start: 4
• Page End: 7
• Publication Date: 2014-01
• Subjects: Ophthalmology -- Periodicals; Eye -- Diseases -- Periodicals; Eye -- Surgery -- Periodicals; 617.7005
• DOI: 10.3109/08820538.2013.810288
• Languages: English
• ISSNs: 0882-0538

Abstract

<abstract> <title>Abstract</title> <p> <italic>Presentation of suspected pediatric uveitis</italic>: Pediatric uveitis is usually managed in specialized ophthalmic centers in the UK. Meaningful data acquisition in these clinics may be helpful in clinical governance, and healthcare planning in a specialty that is gradually changing due to changes in treatment choices. <italic>Methods</italic>: Retrospective analysis of prospectively acquired data in the Liverpool pediatric uveitis database was performed. <italic>Results</italic>: Analysis of our data, based on 147 patients, with a mean age of 10 years, indicated a female to male ratio of 2:1. 99% of patients were Caucasian. Our data indicates 86% of all patients attending the uveitis clinic were diagnosed with juvenile idiopathic arthritis, followed by intermediate uveitis 5% and idiopathic uveitis 4%. 46% of patients required treatment. Systemic treatment included methotrexate (34%), prednisolone (14%), etanercept (6%), ciclosporin (6%), mycophenolate (3%), and infliximab (1%). Severe visual loss (defined by counting fingers or below vision) was seen in 10 eyes despite appropriately treated chronic uveitis. <italic>Conclusion</italic>: Our data shows uveitis-related ocular morbidity in a predominantly pediatric Caucasian population. Patients with severe and chronic uveitis may experience significant uveitis-related complications and subsequent visual loss despite aggressive treatment.</p> </abstract>