Analgesic Effects of Microwave Ablation of Bone and Soft Tissue Tumors Under Local Anesthesia. Issue 12 (23rd September 2013)

• Record Type: Journal Article
• Authors: Kastler, Adrian; Alnassan, Hussein; Pereira, Philippe L.; Alemann, Guillaume; Barbé, Daniel‐Ange; Aubry, Sébastien; Tiberghien, Florence; Kastler, Bruno
• Is Part Of: Pain medicine. Volume 14:Issue 12(2013)
• Page Start: 1873
• Page End: 1881
• Publication Date: 2013-09-23
• Subjects: Pain -- Periodicals; Pain -- Treatment -- Periodicals; Analgesics -- Periodicals; Pain -- Periodicals; Pain Management -- Periodicals; Douleur -- Périodiques; Douleur -- Traitement -- Périodiques; Analgésiques -- Périodiques; Analgésique; Soulagement de la douleur; Périodique électronique (Descripteur de forme); Ressource Internet (Descripteur de forme); 616.047205
• DOI: 10.1111/pme.12242
• Languages: English
• ISSNs: 1526-2375

Abstract

<abstract abstract-type="main"> <title>Abstract</title> <sec id="pme12242-sec-0001" sec-type="section"> <title>Objective</title> <p>To assess the feasibility and efficacy of microwave ablation (MWA) of painful refractory bone and soft tissue tumors performed under local anesthesia.</p> </sec> <sec id="pme12242-sec-0002" sec-type="section"> <title>Study Design</title> <p>A retrospective study between 2011 and 2013.</p> </sec> <sec id="pme12242-sec-0003" sec-type="section"> <title>Setting</title> <p>A single center, Academic Interventional Pain Management Unit.</p> </sec> <sec id="pme12242-sec-0004" sec-type="section"> <title>Subjects</title> <p>Fifteen patients with 25 refractory painful bone (N = 19) or soft tissue (N = 6) tumors treated with MWA were consecutively included.</p> </sec> <sec id="pme12242-sec-0005" sec-type="section"> <title>Method</title> <p>Local Institutional Review Board approval was obtained, and written informed consent was waived. Lesions included spinal (N = 3), sacral (N = 4), and extraspinal (N = 18) locations. Pain was measured on a visual analog scale (VAS) from 0 to 10 before and immediately after procedure, at 1 week, and on a monthly basis following procedure. MWA procedures were always performed under computed tomography guidance and local anesthesia along with nitrous oxide inhalation.</p> </sec> <sec id="pme12242-sec-0006" sec-type="section"> <title>Results</title> <p>Mean ablation time was 4.09 minutes (range 1–11) with an average of 4.2 cycles with a mean ablation power of 60 W. Preprocedure mean VAS score was 7.2 ± 0.97 (range 6–9). Follow‐up postprocedure VAS scores were as follows: day 0: 1.64 ± 1.86, day 7: 1.82 ± 1.79, month 1: 2.05 ± 2.03 (14/15 patients), month 3: 2.13 ± 1.81, month 6: 2.36 ± 2.17; and were statistically significant (<italic>P</italic> < 0.001). Mean pain relief was 5.5 months.</p> </sec> <sec id="pme12242-sec-0007" sec-type="section"> <title>Conclusion</title> <p>MWA is feasible, safe, and effective in the management of painful refractory bone and soft tissue tumors. It may therefore be considered as a potential alternative to existing percutaneous ablation techniques in the management of bone and soft tissue tumors.</p> </sec> </abstract>