Autism assessment in children with optic nerve hypoplasia and other vision impairments. (3rd September 2013)

• Record Type: Journal Article
• Authors: Williams, Marian E; Fink, Cassandra; Zamora, Irina; Borchert, Mark
• Is Part Of: Developmental medicine & child neurology. Volume 56:Number 1(2014:Jan.)
• Page Start: 66
• Page End: 72
• Publication Date: 2013-09-03
• Subjects: Child development -- Periodicals; Pediatric neurology -- Periodicals; 616.8
• DOI: 10.1111/dmcn.12264
• Languages: English
• ISSNs: 0012-1622

Abstract

<abstract abstract-type="main" id="dmcn12264-abs-0001"> <title> <x xml:space="preserve">Abstract</x> </title> <sec id="dmcn12264-sec-0001" sec-type="section"> <title>Aim</title> <p>This study examined the utility of standard autism diagnostic measures in nine children (aged 5–9y) with severe vision impairment and a range of social and language functioning.</p> </sec> <sec id="dmcn12264-sec-0002" sec-type="section"> <title>Method</title> <p>The Autism Diagnostic Observation Schedule (ADOS) and the Autism Diagnostic Interview, Revised (ADI‐R) were systematically modified and used to assess symptoms of autism in children with vision less than or equal to 20/800, the majority of whom had optic nerve hypoplasia. The results of the assessments, including analysis of symptom patterns, were compared with expert autism diagnoses.</p> </sec> <sec id="dmcn12264-sec-0003" sec-type="section"> <title>Results</title> <p>Modified autism measures demonstrated good agreement with clinical diagnoses. Symptoms found to be most and least reliable in discriminating autism from behaviors common to most children with congenital vision impairment are described. Comparisons of current behavior with parent‐reported behaviors from a younger age suggested that some symptoms of autism in very young children who are congenitally blind may improve with age.</p> </sec> <sec id="dmcn12264-sec-0004" sec-type="section"> <title>Interpretation</title> <p>The ADOS and ADI‐R are useful for clinical assessment and for advancing research efforts to understand autism symptoms in children with vision impairment. However, some autistic symptoms in very young children may change over time, and developmental changes should be closely monitored.</p> </sec> </abstract>